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In particular, the assumption of independent realizations can be problematic for spatial or temporal data, although in principle, adjustments for such difficulties sometimes can be made.
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A spatial error of 0.7° 1.2° would be problematic for research in which high spatial accuracy is required; for example, the particular letter that is fixated on in a word must be strictly distinguished in research on sentence reading.
An important prerequisite for dynamic causal modelling is that each region of a model is identified in each individual subject, which can be problematic for areas that show weak activation levels or inter-individual variability in spatial location.
"This could be problematic for many of our kids.
Endorsing could also be problematic for Mr. Huckabee at Fox.
Personnel issues continued to be problematic for Mrs. Merkel this year.
Why might all of this be problematic for equity investors?
Wound infections may be problematic for physicians.
This might be problematic for Ross.
Academic hassles only appeared to be problematic for younger youth.
Physical and logical guards can be problematic for the Zukin.
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