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However, the equation proposed by Flesch-Janys et al. (1996) may be problematic for ages > 60 years because very small variations in the elimination rate could lead to substantial divergence in half-life length, as observed in the case of 1,2,3,7,8-PeCDD.
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Thus, the presence of apoptosis should not be problematic for ageing.
Kivisild et al. [ 30] advocated the use of only synonymous diversity for estimation of the TMRCA, which is problematic for age estimations in young lineages, while Soares et al. [ 31] implemented a correction for the purifying selection effect on the mutation rate estimated for the entire molecule.
The majority of studies used age-heterogeneous samples, which can be problematic for a number of reasons.
Choosing the book can be problematic for some book groups.
But the antibody test can be problematic for several reasons.
This might be problematic for Ross.
Wound infections may be problematic for physicians.
This may be problematic for many reasons.
Discrimination between seedling and dormant age classes and the adult and flowering classes was problematic for most of the tested indices.
Applying active ageing to a mere economic or physical framework is problematic for several reasons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com