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Temporal comparisons of data sets may also be problematic and require establishing a consistent and comparable measure of stress resistance that can easily translate into ecologically meaningful estimates to relate to climate (Chown et al. 2009; Rezende et al. 2011; Overgaard et al. 2012).
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However, as no validated scales for efficacy for the different behaviours exist, claims as to the relative base level of efficacy for a sample will be problematic, and requiring manipulation avoids these problems by enabling comparison of performance of fear appeals under low and high levels of efficacy.
However, there were a few items, especially in the perception of management factor (Table 6) that were problematic and require additional investigation and refinement.
Diagnosing primary sclerosing cholangitis (PSC) is problematic and requires meeting a burden of proof through clinical, biochemical, radiologic, and histological features.
Thus, estimation of coseismic temperature using the kinetic model of Sweeney and Burnham (1990) is problematic and requires further investigation.
Deviation from an accepted theoretical framework is problematic and requires explanation, such as the explanations offered for the division of cognitive labor.
However, translating this experimental finding into implications for field exposure is problematic and requires more research.
It was mandated that patients have tumours that were problematic and requiring intervention for the local problem.
Re-use of routine data is problematic and requires detailed knowledge of the datasets and their idiosyncracies.
The potential for human exposure to benzene is well established, but quantifying exposure for population-based epidemiologic studies is problematic and requires immense resources.
It is well known that mixing at high loadings is problematic and requires more power to efficiently stir highly viscous slurries.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com