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Providing information to patients about clinical issues for which there is no established evidence base can be problematic, and it is understandable that GPs' discussions could reflect their clinical experience and personal opinion.
To some extent, research has identified aspects of sickness certification that physicians consider to be problematic, and it is also recognized that these can differ between physicians [ 11, 18], whereas very little is known about how physicians respond to the problems that they experience.
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Re-imagining the prison system with the private sector is problematic and it's a liability that we shouldn't easily disregard.
However, the test set up is problematic, and it is anticipated that health monitoring would need tuning for each individual machine.
It is important to look beyond these symbols and understand what is really happening in Europe in general and in Switzerland in particular: while European countries and citizens are going through a real and deep identity crisis, the new visibility of Muslims is problematic – and it is scary.
Both formulations are problematic and it is beyond the scope of this entry to discuss their respective problems at length.
The phrase "deaf-mute" is problematic, and it is not an appropriate way to discuss a person.
In general, implementation processes are problematic and it is often difficult to know to what extent they have been successful [ 21].
However, suicide after absconding is problematic, and it is clearly a challenge to prevent patients leaving a general psychiatry open ward.
Because the approaches vary from one country to another, estimates regarding the prevalence of use and harms associated with use are problematic, and it is currently not possible to make international comparisons (Sumnall et al., 2013).
Until we are given an explanation of why this kind of enhancement is problematic (and it couldn't be problematic because it threatens, say, openness to the unbidden), it is hard to take these worries as presenting any kind of general argument against biomedical enhancement.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com