Sentence examples for be primary mediators of from inspiring English sources

Alterations in histone modifications appear to be primary mediators of epigenetic inheritance in cancer cells [ 39- 41].

Our RT-qPCR data suggests that NOTCH2 and HEY1 may be primary mediators of Notch signaling in canine OSA as well.

Moreover, astrocytes may be primary mediators of changes in local CNS blood flow in response to changes in neuronal activity [ 112].

Calcium/protein kinase C PKC) and calmodulin-dependent kinase II (CaMKII) were considered to be primary mediators of this signaling pathway [ 12, 13].

Furthermore, astrocytes appear to be primary mediators of changes in local CNS blood flow in response to changes in neuronal activity (Schummers et al., 2008; Wolf and Kirchhoff, 2008; Koehler et al., 2009).

These results reinforce the hypothesis that antioxidants are primary mediators of the conditioning effect.

Receptor tyrosine kinases (RTKs) are primary mediators of many of these signals and thus determine the fate of the cell: growth, differentiation, migration, or death.

NK cells are primary mediators of ADCC activation by binding of the Fc part of antigen-loaded antibodies to surface-expressed FCγRΙΙΙa 15.

Compounds that modulate the Hh, Wnt, TGFβ, FGF, or Notch pathways will first be described, since these intercellular signaling mechanisms are primary mediators of tissue patterning and regeneration.

Longitudinal studies using repeated measures of self-management are needed to definitively determine whether decreased levels of self-care and adherence are primary mediators of the association between relationship style and mortality.

Tyrosine kinases are primary mediators of the transmission of extracellular signals into the cell and therefore control many crucial functions including cell differentiation, growth and migration, depending on the signal received from the specific receptor (Levitzki, 2002).