Sentence examples for be prevented by selective from inspiring English sources

Excitotoxicity is defined as neuronal cell death mediated by hyperactivation of glutamate receptor subtypes and therefore might be expected to be prevented by selective glutamate receptor antagonists.

This pathway is becoming of increasing importance due to gaining insight into its prominent role in many developmental processes, and in the maintenance of the malignant phenotype in a wide variety of human cancers, whose growth has been found to be prevented by selective inhibition of constitutive HH pathway activity [14], [35], [36].

The decrease of DA in NAcc below basal levels can be prevented by selective depletion of DA in vmPFC (Pascucci et al. 2007; Nicniocaill and Gratton 2007).

Therefore, part of the side effects of anti-TNF therapies (e.g. appearance of psoriatic-like lesions) might be prevented by selective inhibition of TNFR1 (Van Hauwermeiren et al, 2011).

We observed that versican G3 enhanced cell invasion could be prevented by selective EGFR inhibitor AG1478 (2 μM), selective MEK inhibitor PD 98059 (50 μM), and selective AKT inhibitor Triciribine (2 μM).

Alternatively, self-targeting may be prevented by selective self vs. non-self mechanisms, such as variations in spacer flanking sequences [ 63].> This study describes a comprehensive survey of CRISPR-Cas systems among a large collection of strains from a cosmopolitan marine actinomycete genus.

In SNX reduced myocardial capillary supply is prevented by selective blockade of the sympathetic and endothelin systems [16], [45] as well as by the antioxidant vitamin E [46] but not by ACE-I [16].

These responses were prevented by selective inhibition of COX-2 activity by rofecoxib [ 18].

This observation was prevented by selective EGFR inhibitor AG1478, selective MEK inhibitor PD 98059, and selective AKT inhibitor Triciribine, but not by selective JNK inhibitor SP 600125.

Recently in rat, it was demonstrated that analgesic central effects of celecoxib were prevented by selective μ- β-funaltrexamine) and δ-(naltrindole), but not ĸ-(nor-binaltorphimine) opioid antagonists, after intracerebroventricular administration [ 27].

In both conditions this hyperglycemic effect of PVN stimulation could be prevented by a selective denervation of the sympathetic autonomic input to the liver [21].