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It is estimated that around half of all cancers could be prevented by modification of lifestyle risk factors (Cancer Research UK, 2008b).
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The results of the Finnish Diabetes Prevention Study (DPS) provided the first convincing evidence from a proper randomized controlled trial that type 2 diabetes can be prevented by lifestyle modification (21).
Respiratory tract infections (RTIs) account for the majority of morbidity and mortality during infancy and thus pose a worldwide burden that can be prevented by the modification of environmental factors [ 3, 4].
The study conducted by Tuomilehto et al. (2001) provided evidence that T2DM, in both women and man at high cardiovascular risk, can be prevented by lifestyles modifications, with a decrease of overall incidence of diabetes of 58% [ 39].
The inability of cells to establish filopodia attachment on a nanolandscape might be prevented by a surface modification with ligands.
According to this, it was currently estimated that many cancer-related deaths could be prevented by adequate lifestyle modifications, particularly changes in diet or nutrition [ 12].
This post translational modification could be prevented by inhibition of farnesyl transferase leading to protein activation.
As the effect of 20 4 LPC on IL-8 mRNA induction could not be prevented by coincubation with the antioxidant Trolox, oxidative modification of 20 4 LPC was not likely to account for the observed kinetics of IL-8 increase (Suppl. Fig. 2).
We hypothesized that further chromatin activation upon decreased levels of markers of constitutive heterochromatin may be prevented by increased levels of the Polycomb-dependent repressive H3K27me3 modification.
Total or selective protein extraction and purification should not introduce protein modifications, and endogenous enzymatic activities need to be prevented by adding inhibitors.
This modification confers resistance to proteolysis, rapid aggregation and neurotoxicity and can be prevented by QC inhibitors in vitro and in vivo, as shown in transgenic animal models.
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