Sentence examples for be prevented by blockade from inspiring English sources

Further, our studies show that the loss of surface mGluR1 can be prevented by blockade of either NMDAR or VDCC, paralleling our observations with respect to Homer1b declustering; it may therefore be inferred that loss of synaptic Homer1b is a key event in the downregulation of surface levels of mGluR1.

Development of acid-induced hyperalgesia can be prevented by blockade of neuronal activity in the rostroventral medial medulla (RVM), a site known to facilitate nociception, during the second acidic saline injection, but not during the first, suggesting alterations in the RVM in response to the first injection (male rats) [ 16].

However, hypoxic injury was prevented by blockade of voltage-gated sodium channels, inhibition of calpain and removal of extracellular calcium.

The sinus nerve responses to H2S donors were prevented by blockade of the transmission between type I cells and the afferent terminals, as was the response to hypoxia.

Acidic pH increased [Ca2+]i and decreased p-ERK expression in WT FLS; these effects were significantly smaller in ASIC3-/ FLS and were prevented by blockade of [Ca2+]i.

Specifically, we showed that activation of ASIC3 by acidic-pH increases (Ca2+ i in FLS, which subsequently reduces phosphorylation of ERK and this reduced p-ERK is prevented by blockade of PP2A.

Arnsten and Dudley [ 66] have shown that the PFC-enhancing effects of methylphenidate are prevented by blockade of either NE alpha-2 or DAD1 receptors, suggesting that stimulants facilitate endogenous stimulation of D1 and alpha-2A receptors in the PFC.

The rise in the extracellular concentration of ATP during ischaemia is sufficient to activate P2X7 receptors and kill neurons and oligodendrocytes, an event that is prevented by blockade of P2X7 receptors (Domercq et al., 2010; Arbeloa et al. 2012).

In a study by de Novellis et al., apoptotic pathways were activated in rat spinal cord of sciatic nerve chronic constriction injury (CCI), and the early overexpression of proapoptotic genes and morphological changes in dorsal horn were prevented by blockade of glutamate mGlu5 receptors [ 3].

Although its refineries and storage depots are full of fuel, the country has been prevented by blockades from delivering the fuel to service stations.

Both diabetes and hyperglycaemia induce functional abnormalities in ventricular myocytes, which can be prevented by AngII blockade [ 117].