Sentence examples for be present in tumor from inspiring English sources
We hypothesized that mutations in GNAQ may also be present in tumor types from non melanocytic origin where they could represent alternative route to MAPKinase activation.
In many oncological applications, genetic and population phasing is of little value because of the large number of somatic mutations that may be present in tumor cells.
Allelic loss at each microsatellite locus was considered to be present in tumor samples' DNA when there was at least a 65% peak reduction at one of a pair peak compared with the corresponding peak of normal DNA.
On this basis, it may be understood that genetic ablation gene therapy strategies may be most successful when such strategies are designed to correct one, or more, of the specific genetic changes known a priori to be present in tumor cells.
This suggests that Treg cells are subject to the most prominent constriction of the TCR repertoire and further implies that many TCRs expressed in control lymph nodes (and in healthy mice) will not be present in tumors (Fig. 4A).
This suggests that different carcinogenetic pathways may be present in tumors that are otherwise similar for histology and location.
LCLs seem most appropriate as a model for chemotherapeutic toxicity and, to some extent, chemotherapeutic response, although they do not contain the extensive somatic mutations known to be present in tumors.
In ∼50% of patients with Hodgkin's lymphoma (HL), the Epstein-Barr virus (EBV), an oncogenic herpesvirus, is present in tumor cells.
This is supported by our observation that in five cases mutations in the N-RAS gene were present in tumor cell lines but not in the corresponding tissue samples.
To examine which PFK1 forms are present in tumor cells, four different neoplastic cell lines that are known to induce metastatic tumors after insertion into test animals were used.
Of interest, ME2 is present in tumor mitochondria in levels proportional to the rate of cell division [9], [10], while curiously it is essentially absent in liver, regenerating liver, and the mitochondria of other organs.
