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It is well established that plasma contains circulating nucleic acids; however, until very recently, they were assumed to be present at extremely low concentration and were highly degraded due to the presence of circulating ribonucleases [9].
Perhaps most intriguing is the observation that not only does Pup∼KasB not accumulate in an mpa mutant, but Pup∼KasB appears to be present at extremely low to undetectable levels in this strain (Fig. 3C).
Because they may be present at extremely low concentrations, the identity and concentrations of those gases are not yet known.
Thus, native G72 protein, if expressed at all, appears to only be present at extremely low levels that may not be physiologically relevant.
Whether in the extracellular spaces or within cells, free formaldehyde will be present at extremely low concentrations, since it first reacts reversibly with water to form an acetal (i.e., a more chemically correct designation of the hydrated form than methanediol) and then interacts with glutathione (GSH) to form a thioacetal.
29– 47 The analysis of lymph MM RT-PCR gave more consistent data, which may be related to high volume of lymph fluid in patients with confirmed lymphatic dissemination of the disease (in the blood tumor cells may be present at extremely low concentrations and tumor shedding may be intermittent) and using multiple target markers, including tyrosinase, MART1, and uMAGE.
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However, the elimination of emerging contaminants (ECs), which are present at extremely low concentrations in waste water treatment plants (WWTP) effluents might be accomplished at much lower catalyst (TiO2) concentrations.
Nonetheless, when the purpose of eliminating emerging contaminants in municipal wastewater treatment plant effluents is for reuse of the water, and they are present at extremely low concentrations, a tertiary treatment with a much lower photocatalyst concentration might be possible.
Haplogroups A5a and Y2 are found almost exclusively in Korea but were present at extremely low frequencies.
For example, the inducible Hsp70 (Hspa1a) is present at extremely low levels in brain, whereas the constitutively expressed Hsp90, Hsc70 an Hsp60 are easily detected [90].
NIK is predominantly regulated at the post-translational level and is present at extremely low levels in most cell types.
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