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However, implant surgeons should be prepared for bone graft during implant surgery because more and more complicated patients could visit their clinics.
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As a result, a biocompatible scaffold with good cell attachment, facility in formation in desired shapes and simplicity in production were prepared for bone tissue engineering.
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In the present study, biomimetic composite scaffolds of collagen and biphasic calcium phosphate nanoparticles (BCP NPs) with a controlled release of dexamethasone (DEX) and the controlled pore structures were prepared for bone TE.
The fresh extraction sockets were prepared for bone grafting.
The nonunion site was prepared for bone grafting by fish scaling (cortical flaps) and multiple drill holes.
One week later, the antibiotic beads were removed and the defect was prepared for bone graft placement.
ALN-PEG2k-ALN-modified calcium phosphate nanoparticles (APA-CPNPs) with an ALN targeting moiety and hydrophilic poly (ethylene glycol) arms tiled on the surface was prepared for bone-targeted drug delivery.
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