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Additionally, intermediate CpG islands may be preferential targets for de novo methylation in somatic cells during development [27].
Cellular carboxyl groups have been previously reported to be preferential targets for alkylation by nitrosoureas.
The clearest cases of physical independency between maturity and late blight resistance QTLs could be preferential targets for introgression into elite cultivars for late blight resistance breeding.
Therefore, cancer types where the presence of Tregs is of poor prognosis could be preferential targets for CD70-targeted TRAIL fusion proteins.
Indirect immunodetection and confocal analysis (Fig. 2D G) performed 72 h later suggested that neurons might be preferential targets for CPP-Cre internalization, based on the morphology of the expressing cells (Fig. 2D, E) – consistent with previous observations [ 37].
The idea that different regions of the bacterial chromosome may be preferential targets for a specific subset of regulatory genes is also supported by the high level of conservation of a gene's position with respect to the distance from the origin of replication in the family of gammaproteobacteria (Sobetzko et al. 2012).
Similar(53)
Recent research has demonstrated that strong CpG island promoters are mostly unmethylated, even when inactive, whereas CpG poor or weak CpG island promoters are largely hypermethylated, or are preferential targets for de novo methylation in human, respectively (Weber et al. 2007).
Interestingly, our finding that HOX gene clusters were preferential targets for DNA methylation is consistent with a previous report [ 40].
These amino acids are essential for enzymatic activity and are preferential targets for covalent modification by electrophiles.
Immunodominant regions are preferential targets for T‐cell responses because they are immunogenic in most individuals within a cohort.
These conserved residues are preferential targets for future mutagenesis experiments to determine the importance of the Transposase_21 domain for TNPD function, as they are expected to abolish or significantly alter the domain functionality.
Related(15)
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