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Characteristics found to be predictive of risk at the P < 0.01 significance level in age- and sex-adjusted models were entered simultaneously (together with age and sex) into a single model.
In a study by John et al. [ 93], the ability of tumour fragments from patients undergoing curative surgery to engraft into primary tumour xenografts was found to be predictive of risk of disease recurrence.
The four intrinsic subtypes of breast cancer, defined by differential expression of 50 genes (PAM50), have been shown to be predictive of risk of recurrence and benefit of hormonal therapy and chemotherapy.
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Both a rapid PSA velocity (rate of rise) and short PSA doubling time (PSADT) have been proposed as biomarkers to predict local versus distant metastases, and PSADT has additionally been predictive of risk for metastatic progression and cancer-specific mortality.
Quantification is clinically useful because higher CSF CRAG titers are predictive of risk for death (15 – 17 ), and higher serum CRAG titers predict risk for immune reconstitution inflammatory syndrome (IRIS) (18 ).
They tend to ship with a lower number of shipments, or maybe have many transient partners.Even the very structure of a supply chain is predictive of risk.
After adjusting for age, gender, diabetes duration, glycated hemoglobin levels, blood pressure, body mass index, and pubertal stage, larger arteriolar caliber was predictive of risk of diabetic retinopathy (odds ratio, 1.44 per SD increase in arteriolar caliber; 95% confidence interval, 1.11-1.86).
Interestingly, they demonstrated that HIS was predictive of risk of breast cancer metastasis in large cohorts of patients.
A patient's clinical and biological features are predictive of risk of relapse and determine the aggressiveness of the prescribed clinical treatment protocol.
Even if several studies concur that measures of delayed recall are predictive of risk for developing dementia [ 14, 48], other have found that measures of learning are equally or more predictive [ 49, 50].
The models are only used as a convenience in calculating the risk scores to create a categorical variable, which is predictive of risk of recurrence or censoring, to implement the weighted KM method.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com