Other than classifying sera as INNO-LIA reactive or nonreactive, no banding pattern or algorithm could be derived that would have been predictive of infection of any given primate species.
A CRP concentration >5.0 mg/dl at day 6 was predictive of infection with a sensitivity of 85% and a specificity of 62% (positive likelihood ratio 2.2, negative likelihood ratio 0.2).
Mikolajczyk et al [ 18] investigated whether contact counts for a group of school children in Germany were predictive of infection in the past 6 months, with no effect of household size or contacts observed.
A CRP concentration > 5.0 mg/dl at the D6 was predictive of infection with a sensitivity of 85% and a specificity of 62% (positive likelihood ratio 2.2, negative likelihood ratio 0.2).
In univariate analysis, only 2 factors were predictive of infections.
At the patient level, no variable (age, sex, underlying rheumatic disease type and duration, bronchiectasis disease duration and number of previous DMARDs) was predictive of infections.
Procalcitonin variation between D-1 and D0 was calculated in 45 patients and was also found to be predictive of nosocomial infection (AUROCC = 0.89; 95% CI, 0.79 0.98) with a 100% positive predictive value if the +0.26 ng/mL threshold value was applied.
Only two specific practices, using a communal laundry and not using bleach in communal laundering, were found to be predictive of increased risk of infection.
For example, nucleotide polymorphisms in or near the gene for the type III IFN, IL-28B, were recently shown to be predictive of resolution of acute HCV infection, or favorable response to IFN-alpha/ribavirin therapy in infected patients.
Combined, these data all suggest very early divergence in immune responses to SIV infection could be predictive of disease outcome and vaccine efficiency.
