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These inflammatory parameters have been reported to be predictive markers for cancer prognosis.
These molecules have important implications in docetaxel-induced cell death and can be predictive markers for docetaxel-based chemotherapy.
In order to be predictive markers for metastasis, the marker must be somehow specific to metastatic cells.
We evaluated them retrospectively to determine whether their expression levels would be predictive markers for a response to S-1 and/or prognostic markers.
As for matrix metallopeptidase-2 (MMP-2) and metallopeptidase-9 (MMP-9), they contribute greatly to tumor metastasis and invasion and are considered to be predictive markers for cancer.
While samples from treatment-naïve patients are not available and all patients included in this study received chemotherapy, the identified factors may be predictive markers for chemotherapy (FOLFOX/XELOX) outcome or disease progression.
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Peng, S. Y., Lai, P. L., Pan, H. W., Hsiao, L. P. & Hsu, H. C. Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis.
In patients with type 2 diabetes mellitus (T2DM), hypertension and microalbuminuria are predictive markers for increased renal and cardiovascular risk.
KRAS mutations are predictive markers for the efficacy of anti-EGFR antibody therapies in patients with metastatic colorectal cancer.
In HCC, some deregulated lncRNAs are predictive markers for precise tumor stages and, most importantly, they have been characterized as tumor suppressor and/or oncogenes.
The results of this study suggested that MDM2 and p16 are predictive markers for chemoradioresistance in cStageIII ESCC and Ki-67 is a prognostic marker following dCRT in cStageIII ESCC.
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