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Based on conventional wisdom, the amino acid divergence of this synthetic HA 1 5 con gene would not be predicted to induce protection against H1 influenzas.
Our discovery of a link between N-Myc and lif in neuroblastoma also suggests a possible new treatment for neuroblastoma in the form of LIF antagonists that would be predicted to induce regression through stimulating differentiation (Fig. 6).
The c.2268dup can be predicted to induce a frameshift in the normally spliced product and the appearance of a premature termination codon (PTC) at position 757 p.Glu757X).
We therefore asked whether the nocodazole conditions used in our experiments induced DNA damage, which would be predicted to induce Ku-dependent activation of DNA-PKcs.
If demethylation of promoter DNA can influence transcription of the BRF2 gene, then treatment with the methylation inhibitor 5-azacytidine might be predicted to induce expression.
Finally, P27 is located in the center of TMD1, and it would be predicted to induce a 30° bend in the helix.
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While PD patients showed 319 AS events compared to controls, DBS-induced response of 254 AS changes overall, 44 of which were predicted to induce NMD at the protein level.
This construct is predicted to induce formation of hairpin mRNAs carrying the fragments of OsWRKY IIa genes in the stem and the GUS spacer in the loop.
This feedback between the presence of benthic primary producers such as seagrass and the consequent light environment has been predicted to induce bistable dynamics locally.
Since it is generally agreed that size thresholds limit differentiation rates [20], [21], [23], an early cue indicating a potentially severe time constraint on development and requiring its acceleration is predicted to induce accelerated growth so that differentiation remains unconstrained.
To achieve this balance, the projection tips for this experiment were designed to be sharp, tapering down to <1000 nm at the tips, which, when applied to skin at low speeds (∼1 m/s), were predicted to induce minimal cell death [17], [18].
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