Sentence examples for be predicted to downregulate from inspiring English sources

Since lin-41 null mutant oocytes do not as a rule progress to diplotene or diakinesis, they might not be predicted to downregulate RNA polymerase II transcriptional activity after pachytene.

Copy-number gains of NR0B1 were predicted to perturb testicular development by downregulating the protein expression of SF1, WT1, and SOX9 [18].

We knocked down expression of 14 of these genes, seven of which were predicted to be upregulated and seven downregulated during regeneration based on the microarrays.

Of more than 500 miRNAs assessed, formaldehyde significantly downregulated 89 that are predicted to influence molecular signaling pathways relevant to cancer, inflammatory response, and endocrine system regulation, potentially representing a first step on the path toward disease.

When comparing this list with the list of miRNAs predicted to be targets of miR-203 using several miRNA target prediction software packages, we found that ∼25% of the mRNAs downregulated by ING1b were predicted to be target genes of miR-203 (301 of 1199 genes; Figure 2A).

The intersection in Venn diagram between three lists, identified 210 common genes, that is, genes that were downregulated upon miR-320c overexpression, downregulated during adipocytic differentiation of hMSCs and that were predicted to be targeted by miR-320c in silico.

Using Chromatin Immunoprecipitation (ChIP), we show that RGL2 directly downregulates at least one cell wall modifying enzyme, which is predicted to constrain cell growth thereby leading to inhibition of seed germination.

On the basis of this analysis, 5 of the 18 miRNAs downregulated in SSEA4-positive cells (miR-96-5p, miR-200c-3p, miR-429c-3p, miR-92a-3pnd miR-92a-3predictededictod targetget ST3GAL2, suggesting that SSEA4 expression is regulated posttranscriptionally.

And the trend is predicted to continue.

Furthermore, KLF2, which downregulates PAI-1 expression and negatively regulates pro-inflammatory activation of monocytes through inhibition of NF-κB and AP-1 [ 4], was predicted to be activated exclusively in the GE-RES group.

As would be predicted, A-83-01 treatment downregulates the expression of well recognized markers or regulators of EMT and TGFβ signaling to levels similar to or below that seen in differentiated P0 RPE.