Your English writing platform
Discover LudwigExact(13)
Once a single T cell epitope is defined, by holding its TCR-facing residues constant and allowing its MHC-binding residues to vary, it becomes possible to search protein sequence databases for epitopes that appear "homologous" to a given TCR, despite minor variations in MHC binding residues, that will still be predicted to bind to the same MHC.
For GCC185, the N-terminus would therefore be predicted to bind vesicles.
The resulting ADP-bound BiP would be predicted to bind the unfolded substrate with high-affinity (2).
This suggests that in cattle γδ T cells play a more important role in immune function since they would be predicted to bind a greater variety of antigens.
A small molecule ligand that optimally reproduces both of these interactions could be predicted to bind tighter to the IN active site, regardless of local sequence variations.
NvTSP168100 has a canonical laminin G domain-like N-terminal domain containing motifs rich in basic residues and can be predicted to bind heparan glycosaminoglycans.
Similar(46)
a NSC11668 is predicted to bind the ATP-binding pocket.
In the docking model, FK-A11 was predicted to bind to the ATP-binding site of p110α, similarly to FK228 and FK-A5.
There are three other miRNAs miR-34a, 449a and b that are predicted to bind to the same binding site according to the TargetScan.
Of these, 13 topologies were predicted to bind in the heparin-binding site of heparin cofactor II at a ∼60° angle to helix D, a novel binding mode.
Normally, IL-10 is predicted to bind to A2M with a binding energy score of -39.2.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com