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Thus, before the BER capacity of a cell can be predicted or modulated, a better understanding of Pol β and PARP activity-independent BER pathways is required.
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The heightened pro-inflammatory response during the post-burn period would be predicted to modulate leptin levels.
DOI: http://dx.doi.org/10.7554/eLife.01293.005 In subsequent experiments, we examined two opposed ways in which CoA can be predicted to modulate the MEND pathway, assuming that CoA is first used to generate acyl CoA from fatty acid and subsequently is released during palmitoylation of membrane proteins.
Although QDs have been predicted to be modulated at very high frequencies theoretically, it has been shown by Deppe et al. [4] that the current densities required to reach these values should be considered.
As was predicted, feedback valence modulated activation in each of the striatal ROIs.
Specifically, tumors with dysregulation of genes that are modulated by treatment of rapamycin will be predicted as "sensitive" or "resistant" based on their correlation to gene dysregulation from rapamycin treatment in the Connectivity Map data.
This 3'UTR 460 T>C variant was predicted to modulate the binding of several micro RNAs.
This representation may allow for the most interesting observations to be made: compounds that are predicted to modulate similar protein targets, and thus potentially share similar modes of action, are clustered together; if similar interactions are observed consistently between clusters, the underlying modes of action of each cluster might be hypothesized to interact as the cause of the synergy.
Another of the highly expressed miRNAs, miR-146a is predicted to modulate NK cell signaling and IL-4 signaling pathways.
Collectively, these molecules are predicted to modulate the expression of many human genes.
Members of the ABF/AREB family have been shown to interact with diverse proteins that are predicted to modulate their transcriptional activity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com