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For a multiple-component mixture (MCM) system with a definite chemical composition, the mixture toxicity can be predicted only if the global concentration additivity (GCA) is validated.
A potential fusion will be predicted only if reads from both sides of the break points show soft clip evidence to support the event.
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It is easy to see, however, that this is predicted only if 'John came' and 'Bill came' are not taken to be alternative forms.
Failure of clinical trials using current tumor vaccines with monovalent Ag and the lack of PAMP would have been predicted only if the executors had had sufficient knowledge on the innate immune system.
Early in the treatment development phase it makes sense to compare with current practice, especially as some improvement in usual care would be predicted if only because symptoms do get better in time.
One may choose either of the given prediction strategies on the server: PSSM profile based model (the best model as default model), Hybrid model (PSSM+SSC) and Consensus method (a sequence will be predicted as cyclin only if both hybrid and PSSM models predict the sequence as cyclin).
One of the earliest examples comes from thermodynamics [ 1], where heat emission spectra could only be predicted correctly if energy "comes in packets", known as "quanta".
A region of the sequence will be predicted to be an CRUNCS only if the conservation observed cannot be explained solely by the need for conservation of the encoded amino acids.
For a protein, whatever how many domains it contained or were predicted, if only two boundaries of one predicted domain were same with those of one correct domain, or its ranges < = +10 aa, this prediction would be as an accurate prediction.
Some can be predicted, others we can only speculate about.
If these stacks are not included, then the pseudoknot will be predicted not to form, and only the stem 1 hairpin will be predicted to form.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com