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Furthermore, proteomics allow the detection of proteins and post-translational protein modifications, which cannot be predicted by microarray analysis and therefore is complementary to gene expression analysis.
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An exception was that five of the probes examined showed a greater degree of downregulation in Crx-/ than was predicted by microarray (see Table S1).
BRCAness in the training set of 84 tumours could accurately be predicted by prediction analysis of microarrays (PAM) (accuracy 94%).
MAP3K7 was predicted by the microarray to be repressed to a greater extent by pulsatile cortisol, and this effect was not confirmed by qRT-PCR measurement.
MAOA was predicted by the microarray to be induced to a greater extent by continuous cortisol, and this was seen by qRT-PCR, though it did not reach statistical significance, and FOXO1 was induced to a similar extent by both pulsatile, and continuous cortisol in both the array, and the qRT-PCR.
For each strain, we chose genes that were predicted by the microarray to have significant changes in transcription.
Differences in glucosinolate biosynthesis and hydrolysis had been predicted by a heterologous microarray study and subsequently confirmed by HPLC.
The effectiveness of using genomic DNA as a reference in the microarray assay was predicted by simulations using the model and parameters described above.
A statistical analysis of the microarrays was performed, and SFPs were predicted by determining the hybridization differences at each perfect match (PM) probe in the array (Thongjuea et al. 2009).
Novel miRNAs were predicted by miRDeep.
No prenylation sites were predicted by PrePS.
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