Future trials should be powered to detect important clinical end points and be designed to avoid premature exhaustion of the filter.
This was used to determine under which operating conditions an electric motor has to be powered to reach the highest efficiency.
If important subgroup effects are anticipated, trials should either be powered to detect them reliably or pooled analyses of several trials should be undertaken.
This review discusses important and clinically relevant outcomes that future trials should be powered to address and identifies the challenges facing the neonatal clinical trials community.
As for the global study, it should be kept in mind that the methods developed for it are not intended to produce representative country samples, and the study will not be powered to produce estimates at country level.
Many project evaluations are statistically underpowered to observe impact on nutritional status, but appear to be powered to observe impacts on food consumption and dietary quality, which we conclude are an appropriate level of impact of agriculture-nutrition projects.
Because it elected to continue operating Envisat until it had too little fuel to be powered to a lower orbit, as international guidelines prescribe, ESA could be held liable for negligence, or even gross negligence, if Envisat or pieces of it damage an active satellite in the 100-plus years Envisat will remain in orbit, according to the IISL analysis.
In order to be powered to detect significant hyponatremia in any treatment arm, the study would have had to include a much larger number of participants, but this was not the primary study aim.
As relative risk and hazard ratios (HR) are not readily comparable, we used the previously reported HR of 1.22 per doubling of Lp(a) level [1] observed in European populations and estimated that we would have to be powered to detect an HR of 1.07 for the corresponding ∼25% change in Lp(a) seen per allele of rs9457951.
The study will be powered to detect a 10% increase in complication rates with NSAID use.
The reviewed studies were not prospectively designed; they may not be powered to assess statistical significance.
