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Previously, a high-content screen with Chlamydia trachomatis-infected cells was performed, and acylated sulfonamides were identified to be potent growth inhibitors of the bacteria.
Out of five different solvent fractions from the leaves of S. grandiflora tested for anticancer activities, methanolic fraction was found to be potent growth suppresser of the human A549 non-small cell lung cancer cell line.
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Bombesins are potent growth factors for murine Swiss 3T3 cells.
The transforming growth factor (TGF -βs are poTGF -βsowth inhibitors of normareepotential cells.
These data demonstrate that BAFF/APRIL are potent growth factors in B cell malignancies.
TGF-alpha is a potent mitogen for epithelial cells, whereas the PDGF isoforms are potent growth factors for mesenchymal cells.
Increasing evidence showed that PDGF is potent growth factor to enhance osteoblastic differentiation in many types of cell [ 31].
On the other hand, BMPs are potent growth factors for bone repair and specifically BMP2 shows excellent ability to induce bone formation of adequate quality.
Since GAs are potent growth stimulating hormones in vascular plants, and Physcomitrella has at least a protein that is closely related to gibberellin receptors, the question is prompted whether or not Physcomitrella can respond to gibberellins.
Stable mutants of QB928 that propagate successfully on 5-fuoroTrp (5FTrp) and 6-fluoroTrp (6FTrp) have also been obtained even though 4FTrp, 5FTrp, and 6FTrp are potent growth inhibitors of the parental QB928 strain.
Estrogen and progesterone are potent growth factors for normal breast epithelium [ 15, 16, 35, 36], which is consistent with our observation that average proliferation was significantly higher in TDLUs from premenopausal than in postmenopausal breasts, which has also been observed by others [ 33, 35].
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