The test compounds showed antiplatelet activity less than the standard drug, however, hydrazone derivatives ZE-4b and ZE-4c were found to be more potent as compared to sulphonamide derivatives.
For instance, in the ancient TCM record "Origins of the Materia Medica" (Ben Cao Yuan Shi, published in 1612) it is mentioned that the roots of A. carmichaelii that have more number of projections and are large in size will be more potent as compared to those which have fewer projections [62].
Further, dimethyl substituted compound (8o) found to be more potent as compared to the single methoxy substituted compounds (8a, 8b and 8c).
Plus, they are potent as shit.
The antibacterial effects of OH are more potent as compared to H2O2 because the former cannot be neutralized by any enzyme [ 33].
The butanol extract appeared to be as potent as gallic acid with a maximum inhibition of 93.88% at 1000 μg/mL which is nearly potent as compared to 93.89% for gallic acid at same concentration.
Present study also revealed that methanolic fraction is more potent as compared to other fractions [33, 34], which have shown that high total polyphenol content increases the antioxidant activity and proves a linear correlation between phenolics content and antioxidant activity.
The TLR9 stimulation is less potent as compared to anti-CD40 stimulation but induced similar IgG levels in patients (2825±594 ng/mL) and controls (3337±1468 ng/mL) (Fig. 2B, right panel).
A VIP analog with multiple N-terminal domains was found to be slightly more potent as compared to [Nle17]VIP towards VIP receptor type 1 (VPAC1)—related cAMP production.
Compound 10a displayed significant inhibition (IC50 ± SEM = 0.25 ± 0.05 µM) that was found ≈168 fold more potent as compared to previously reported inhibitor suramin (IC50 ± SEM = 42.1 ± 7.8 µM).
