Sentence examples for be potent activators of from inspiring English sources

We observed long-chain FAs, such as OA and AA, to be potent activators of the proton transport activity of neuronal UCPs.

Recently, this class of polysaccharide has come under intense study as they have been determined to be potent activators of the innate immune system in invertebrates and vertebrates, and are currently being investigated as promising pharmacological agents for fungal infections and the treatment of many debilitating pathologies such as diabetes and cancer.

The supernatant is rich in cytokines TNF-α, IL-8, IL-6, and IL-1β (Figure 2), which are known to be potent activators of endothelium.

The microbial HSP70s have acquired special significance in immunity since they have been shown to be potent activators of the innate immune system via toll like receptor (TLR -2 and TLR -2signanding [57].

Moreover, NETs can be potent activators of complement, further exacerbating disease [ 68].

In vitro, PDGFR isoforms have been shown to be potent activators of fibroblast proliferation, migration and survival [ 10].

When the α-ketoglutarate concentration was low (0.03 mM), wild-type PII and both of the heterotrimeric forms of PII were potent activators of the AT activity of ATase, consistent with prior results and the results shown in Figure 1.

Early generation vectors based on adenoviruses were potent activators of the innate immune system, activating TLR9, 26 TLR26 26 complement, 27 and the NLRP3 inflammasome.

It is well known that both CDDP-induced DNA damage and CDDP-induced oxidant stress are potent activators of p53 [ 68, 69], and that p53 can in turn activate bax [ 70, 71].

Long-chain fatty acids are potent activators of preadipocyte differentiation.

Unlike heparin, many highly charged polyanionic polymers are potent activators of Factor XII (Hagemann factor), secondarily producing kinins [15].