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In other familial cases of oesophageal cancer and in sporadic cases, a polygenic/multifactorial aetiology can be postulated through sharing of alleles at many loci, each contributing to a small increase in cancer risk.[35] For example, only a subset of familial breast cancer is clearly hereditary, owing primarily to mutations in a single gene.
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Issues of education and place of belonging are postulated through an architectural perspective.
A neural stem cell-mediated peripheral immunomodulatory effect was postulated, through the modulation of macrophage-related TNF-α release.
Various mechanisms have been postulated through which income inequality may manifest an effect on health outcomes [ 10, 14].
Since these syndromes share many clinical features, including generalized pain sensitivity, it is postulated that they share common pathogenetic mechanisms.
From Star Wars, Star Trek, and all the other science fiction movies you may have seen, you probably know that wormholes are postulated pathways through the fabric of space-time so it can be traversed much faster.
Visceral hypersensitivity is postulated to occur through central (spinal cord or brain) or peripheral (within the esophageal wall) processes.
Man inhibition of seed germination has been postulated to act through a hexokinase-dependent pathway.
Interestingly, it is postulated that the sequences that are not shared between human and chimps may be important for human-specific traits [25].
PTPN22/CSK pathway has been postulated as a potential common genetic factor shared for different autoimmune disorders [ 6, 8– 11].
The key virulence factors shared between EHEC 1 and EHEC 2 clonal complexes were postulated to have been introduced through multiple and parallel acquisitions of mobile elements [ 37].
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