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Hence, it may be possible that orphan loss is stochastic and reflects weak purifying selection.
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Thus, as per previous studies, it is possible that honey bee TRGs (orphans and genes limited to the Hymenoptera) are young genes formed via a variety of mechanisms such as gene duplication, exaptation from transposable elements, horizontal transfer, and de novo gene formation [ 14, 29].
Thus, it is possible that at least some of these "orphan" mutation frequency patterns are tissue or cell-type specific.
It is possible that some of these, such as the orphan chemokine CXCL17, recently shown to promote angiogenesis and cancer progression [ 45], could also be involved in regulating metastatic dissemination via the IL-13 pathway.
This is somewhat surprising, since people are typically saddened by the plight of orphans, but it's possible that positive emotions increase risk taking -- including giving to a needy stranger.
While our data suggests that a substantial fraction of P. pacificus orphans originates from insect genomes, it is possible that HGT involves vectors as intermediate carriers.
Thus, it is possible that duplicated genes at subtelomeric regions may serve as a source for species-specific orphan PCGs.
It is possible that there is a selection effect, for example, among respondents who cared for HIV/AIDS infected relatives or those who cared for orphans.
Could that be possible?
Would that be possible?
That may be possible.
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