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In addition, members of the GATA family have been shown to be positive regulators of CLDN11 transcription [28].
As a representative TF set for performance analysis, we selected the 70 TFs with known DNA binding motifs in TRANSFAC [3] that were predicted by ARACNe to be positive regulators of at least thirty targets, thus allowing appropriate statistical power for enrichment analysis.
Through inhibition of YAP, the Hippo pathway kinases should be positive regulators of VGLL4 protein expression.
CPKs have been shown to be positive regulators of race-specific pathogen defense in several plant species [ 32- 35].
Several miRNA are known to be positive regulators of myogenesis [ 33, 34] and DICER1 is essential for muscle development [ 35].
Our results indicated that the DUF642 proteins encoded by At4g32460 and At5g11420 could be positive regulators of PME activity during several developmental processes.
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Previous studies had revealed that Wnt4 might be positive regulator of mitosis and key mediator of apoptosis in mammals.
In summary, only PEP-dependent transcripts were consistently and severely down-regulated in fln seedlings, indicating that FLNs are positive regulators of TAC complex function.
Unlike importin-α, the other two apoptosis-related proteins Annexin A4 and NDUSF3 were both up regulated (1.95 and 1.51 fold respectively), and are positive regulators of apoptosis.
Although supported by the data, the up-regulation of RP genes is unexpected, considering that PKA and TOR are positive regulators of RP genes [ 10, 12].
MYB33 and MYB101, two miR159 targets, are positive regulators of ABA responses during germination and are subject to ABA-dependent miR159 regulation [ 17].
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