The non-reactive nature of Ar–He plasma and solid carbon results in formation of pristine SWCNT final product soot which is insoluble in many solvents and is poorly incorporated in polymers matrix.
The remaining analogs (mostly backbone), although AARS substrates, are poorly incorporated into peptides during translation.
Consistent with the poor trimerization we observed, fibers with zipper domains incorporated into the H-I loop were poorly incorporated into mature virions, with the exception of the fiber containing the E-zipper in the H-I loop (Figure S2).
Similar synthetase engineering may be needed for the N-methyl amino acids, which, except for N-methyl His and Asp were poorly incorporated into peptides in our experiments and were poor AARS competitors as well.
In contrast to thymidine, FLT is poorly incorporated into DNA (Sundseth et al, 1996).
Porphyrin 1 was poorly incorporated in vesicle membranes, but membrane-bound 1 could be observed using fluorescence microscopy.
Indeed, it has been previously reported that several guideline recommendations have been poorly incorporated into the clinical practice after their development and distribution [ 2, 11].
The very-long-chain fatty acid (lignocerate) was poorly incorporated into glycerophospholipids, both endogenously (supplementary material Table S1) and in our labeling study (Fig. 3A).
Accordingly, in cultured cells (19) exposed to an excess of palmitic acid, this fatty acid is poorly incorporated into triglycerides and causes apoptosis, and unsaturated fatty acids rescue palmitate-induced apoptosis by channeling palmitate into triglyceride pools.
Bertozzi and co-workers have previously shown that it is the other way round with azido sugars, and N-azidoacetyl-glucosamine (GlcNAz) is poorly incorporated into the cell-surface glycans of human cell lines, 32 whereas GalNAz is well incorporated, and we have had the same experience.
