Sentence examples for be poor substrates of from inspiring English sources

Carbapenems such as meropenem, doripenem, and ertapenem have been demonstrated to be poor substrates of BlaC.

Cationic amino acids, such as lysine, are poor substrates of LHT1, but are imported by amino acid permease 5 (aAP5) [6], a transporter that efficiently transports cationic amino acids when expressed in oocytes and yeast [7].

In comparison, the conventional antipsychotic haloperidol which displays a high antagonistic activity at dopamine D2 receptors is poor substrate of P-gp.

These data suggest that zymosterol is the crossover point between the Bloch and MK R pathways in these cells under these conditions, and that the methyl sterols upstream of zymosterol are poor substrates for (or do not have access to) DHCR24.

(39) All of the vanilloids were poor substrates for the other LOX enzymes.

The pHAHs fit into the active site for CYP1A but are poor substrates for CYP1A metabolism, causing an uncoupling of electron flow between the enzyme and the substrate.

MRP1 and P-gp have great similarities in both structure and drug resistance, with the exception of taxanes, which are poor substrates for MRP1.

Longer, branched, or secondary alcohols are poorer substrates for ADH1.

However, PUs are poor substrates in supporting the adhesion and growth of vascular endothelial cells.

Moreover, substrate analogs that were poor substrates did not have as large a solent viscosity effect.

In contrast, N-methyl-substituted ynamides were poorer substrates (entries 5 and 6): reactions of both methane- and 4-nitrobenzene sulfonamides 1 e/f were slow; products 2 e/f were only isolated in low yields, and similar quantities of the regioisomers 3 e/f were observed.