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The prototypical SR protein ASF/SF2 (human alternative splicing factor) contains two N-terminal RNA recognition motifs (RRMs) (RRM1 and RRM2) and a 50-residue C-terminal RS (arginine serine-rich) domarginine serine-richphorylatedomainumerous serines by thatprotein kinase SR-specanic protein kinase (SRPK) 1.
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KaiC is an autokinase and autophosphatase that can be phosphorylated at two adjacent residues: S431 and T432.
Paxillin, in contrast, was found to be phosphorylated at Tyr118 when membrane associated (Fig. 4b) and localized near ITGαVβ3 exclusively in AT-cells (Fig. 4c, arrowhead).
This implies that Synj is likely to be phosphorylated at multiple sites, but the p-Synj antibody may not be able to distinguish between all the sites.
Yeast 26S proteasome has been shown to be phosphorylated at low stoichiometry (Wu et al., 2011).
Western analysis and chemical stability studies showed the AGT protein to be phosphorylated at tyrosine, threonine, and serine residues.
STX1 can be phosphorylated at residues other than Ser14.
P01233 can theoretically be phosphorylated at three sites.
While Hsp90beta was phosphorylated at Ser 226/Ser 255 in untransformed cells, phosphorylation was absent in leukemic cells.
STAT proteins, upon being phosphorylated at activating residues, translocate from the plasma membrane to the nucleus where they drive numerous gene programs critical to immune function [10].
Thus, there are numerous target sites that upon Etoposide treatment are bound by p53 that is phosphorylated at S46 to a higher extent than upon Actinomycin D treatment.
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