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Ordering will be performed using randomised numbers for each month and the calls will be made in this order until the required number is achieved.
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The sample ordering was performed using randomised numbers for each month and the calls were made in this order.
An intention-to-treat analysis will be performed using all randomised participants who provide any post-baseline data [ 36].
Assessment of similarity of baseline characteristics across randomised groups will be performed using appropriate summary statistics.
Data analysis will be performed in a blinded manner and main comparative analyses between the two groups will be performed using an intention-to-treat analysis using all randomised participants.
Analyses will be performed using an intent-to-treat principle (ITT) that includes all randomised subjects in the groups to which they were assigned.
Meta-analyses will be performed using a random effects model, when there is little evidence of heterogeneity (I<50%) and only for randomised trials.
A field experiment was performed using a randomised complete block split plot design with three drip irrigation rates (I1: 1.00, I2: 0.80, and I3: 0.60 of the estimated evapotranspiration, ET) and five GB levels (GB0, GB25, GB50, GB75 and GB100, GB levels at 0, 250 50, 75 and 100 mM, respectively) as the main and split plots, respectively.
Meta-analysis was performed using the two randomised studies plus (i) the unadjusted estimate from the non-randomised study and (ii) the reported adjusted estimate, adjusted for baseline differences in the groups.
The main comparison of the primary end point between the study arms was performed using logistic regression using all randomised patients.
A systematic literature review was performed using predefined inclusion criteria to identify randomised, double-blind, controlled trials that evaluated TNFα inhibitors in adult RA patients.
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