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We have presented a registration methodology for accurate alignment between PET and histopathology slices that can be performed in routine pathology settings and that demonstrates an accuracy better than the spatial resolution of the PET scanner.
Image fusion has been impractical and too tedious to be performed in routine work, but in the future, fused images will be used in clinical practice — even in teleradiological consultation.
Visual evaluation of blood smears is regarded as gold standard for detection of EDTA-PTCP, but only a limited amount of smears will be performed in routine laboratories.
We recruited, at random, 2472 asymptomatic subjects aged 30 79 years who underwent thorough annual medical check-ups, in which the subjects underwent a more extensive array of clinical tests than would be performed in routine check-ups, at the Social Insurance Omiya General Hospital, Saitama, Japan, between April 2009 and March 2010.
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As the quantification of the latter parameters is performed in routine when donating blood, a continuous decrease in their level could be interpreted as a premature sign of a later decrease in hemoglobin mass, which is more complex to assess.
All of the investigations were performed in routine diabetes outpatient clinics and were in compliance with the Helsinki Declaration (11).
In all patients, at least one diagnostic CT scan of the chest was performed in routine workup.
In case of tumor heterogeneity, areas with the lowest TSR value were considered decisive as is performed in routine pathology to determine tumor differentiation.
MRD testing was performed in routine diagnostic laboratories, with MRD positivity defined as a level of MRD >0.01% (10−4; that is, >1 in 10 000 cells).
In our test, DNA amplification was performed in routine thermal cycler followed by end-point detection using molecular beacon on dark reader or ELISA reader.
Thirdly, this study was performed in routine conditions, with multiple lecturers who were advised not to modify their sessions with a view to coaching for the test.
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