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The new study raises the possibility that the responders may be patients with the altered genes.
Those who take the drugs for the longest periods of time, and in the heaviest doses, tend to be patients with psychiatric and substance-abuse disorders — a phenomenon that Mark Sullivan, a professor of psychiatry at the University of Washington, has called "adverse selection".
For ethical reasons, the population selected for the initial clinical trials of antiepileptic drugs (AEDs) should be patients with continuing seizures (e.g. no less than two to four partial seizures/month) in spite of several therapeutic attempts using other appropriate AEDs, taken in monotherapy and in various combinations.
And the majority of those who get worse will tend to be patients with arthritis.
We could conclude that some chronic migraine patients refractory for treatment might be patients with IIH.
This reality by itself suggests that the best candidates for use of NS may be patients with the propensity for developing hyponatremia, hypochloremia, and metabolic alkalosis, as seen in severe persistent vomiting.
Examples could be patients with AIDS or organ transplantation [ 1- 3].
The target population will be patients with ESKD on home HD.
The study population is selected to be patients with an expected increased risk of severe hypoglycaemia.
In these circumstances there may be patients with undiagnosed TB, leading to increased risk of infection.
Cases will be patients with primary cancers diagnosed between 1996 and 2011.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com