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Bioavailability in aquatic sediments can be particularly problematic due to their accessibility to food chain biota, and interactions with surface and ground water.
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(muscadine grape) is particularly problematic due to extremely low efficiency, including extended culture durations required for embryo plant conversion.
At the same time, the use of traditional medicines is widespread; this is particularly problematic due to the weak quality control mechanisms in place [ 72].
Women's disagreement with incentive strategies is particularly problematic due to the onus currently placed on women by health services and governments to change their health-related behaviours.
This is particularly true for grasses which represent a number of promising bioenergy feedstocks where quantification of grass lignins is particularly problematic due to the high fraction of p-hydroxycinnamates.
The former species are often acquired by environmental contamination while S. aureus is particularly problematic due to its resistance to antibiotic treatments and ability to reside within mammary tissue in a chronic, subclinical state.
The quantity of infected cells and bacteria typical for each infection is demonstrated in Figure 4. Immune-mediated control of facultative and obligate intracellular bacterial infection is particularly problematic due to the sequestered location and the lack of immune effector access to the pathogens.
Withholding potentially effective treatments due to randomization can be particularly problematic.
Human contamination in other mammalian genome sequences will be particularly problematic, as such contamination is expected to be common due to handling of the samples.
Non-random assignment can be particularly problematic in observational studies comparing older versus newer pharmaceuticals from similar therapeutic classes due to the phenomenon of channeling.
This may be particularly problematic for psychosocial co-morbidities where the prediction of long-term problems is complex due to the subjective nature of symptoms and the multifaceted nature of variables, which might affect their onset.
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