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Gains in body fat may be particularly deleterious for women with breast cancer.
This will be particularly deleterious for those species which have experienced several rounds of genome duplication.
The reasoning here is that captured gene fragments, which can be expressed [ 15, 18], might be particularly deleterious for genome function.
Our results suggest that the influence of early-onset obesity (before 16 years of age) may be particularly deleterious for future diabetes risk for women and could potentially be related to biological factors associated with being obese during pubertal maturation.
This interesting therapeutic conception based on the mechanism of action of AIs may be refuted by arguing that selective inhibition of aromatase could result in temporary accumulation of intraovarian androgens because conversion of androgen substrate to estrogen is blocked by aromatase inhibition, which in turn may be particularly deleterious for women with polycystic ovary syndrome (PCOS).
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The effects of fluorescent light are particularly deleterious for OOK/ASK modulation formats, in which the electrical power spectrum of OOK/ASK contains a strong DC component.
The impact of trade agreements has been particularly deleterious for blue-collar, manufacturing employment.
Hypertension is particularly deleterious for people with diabetes because it confers 2 ∼3 times the risk for cardiovascular morbidity and mortality as for people without diabetes (1, 2).
65 In HIV-infected persons, the effects of TNF-α may be particularly deleterious, as this cytokine has been implicated as a stimulus for HIV expression and for activation-induced T cell apoptosis.
As this microdeletion was in a homozygous form, we predicted that it might be particularly deleterious to the individual and thus selected it for further study, as described below.
Alterations in d-serine concentrations and NMDAr activation during this intense period of embryonic and early postnatal CNS development, induced for instance by perinatal asphyxia, may therefore be particularly deleterious.
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