Sentence examples for be particularly challenging especially from inspiring English sources

For Mr. Reeve, navigating the tides of commercialism while maintaining his clean-cut reputation may be particularly challenging, especially now that he has decided to add commercial directing to his repertory, in a deal with a Manhattan production house, TAG Pictures Inc., announced last month.

This can be particularly challenging, especially for studies in which a clinical team expects that only a few patients will be enrolled per week or per month, which may mean that many samples will be analyzed individually.

The investigation of hearing impairment in infants and young children can be particularly challenging, especially when trying to detect subtle and early toxicity in remote settings where trained audiologists and equipment are not available.

The latter is particularly challenging, especially when associated with tuberculosis scars, which, in our country, have a medium incidence.

Identification and selection of sequences to be used on a microarray are particularly challenging, especially for rapidly mutating viruses.

Ensuring appropriate and uniform good quality training is particularly challenging, especially given many training providers are privately owned [ 49, 56 ], and further research is needed to better understand how to align different actors' motivational interests [ 53 ].

However, generating phantoms with realistic deformations is particularly challenging, especially for the HNC localization, which contains small structures and presents complex anatomical deformations such as melting of the tumor and PG deformation.

Furthermore, it is the experience of the authors that intervening in the school environment in SA is particularly challenging, especially since local and national ministries of education have become far stricter about the implementation of interventions within the school environment, even outside of learning time.

Due to the long latency periods associated with lung cancer, epidemiological analyses are particularly challenging, especially for air pollution where spatial and temporal variation in both residential mobility and air pollution concentrations may produce significant exposure misclassification if not properly incorporated into the exposure assessment approach.

Such cases can be particularly challenging and thus particularly rewarding, personally and professionally.

LPN can be particularly challenging for more complex tumors.