Sentence examples for be overexpressed in multiple from inspiring English sources
MIF has been reported to be overexpressed in multiple cancers and its role in tumor cell proliferation has been documented [ 17, 18, 20, 22].
Using a novel microarray/bioinformatics approach, previously we identified a set of 22 genes that were predicted to be overexpressed in multiple cancers (Reed et al, 2007).
Recent functional studies have confirmed the significance of the physical interactions [ 76]. p97 was also known to be overexpressed in multiple cancers [ 77- 83], pointing to a possible addiction [ 84].
The fact that the murine MVP was found to be orthologous to the earlier described human lung resistance-related protein, known to be overexpressed in multiple chemotherapy resistance models immediately associated vaults with intrinsic drug resistance (Scheffer et al, 1995).
Emerging evidence suggests that targeting Skp2 in human cancers may offer therapeutic benefits in various cancers, as Skp2 has been shown to be overexpressed in multiple types of human cancers.
Although FDPS has been seen to be overexpressed in multiple solid cancers by gene expression microarray (Pilarsky et al, 2004), to our knowledge, this is the first report to determine FDPS protein levels in human cancer tissues.
BST2, which encodes a type II integral membrane protein that inhibits the release of enveloped viruses through its homodimerization36,37, is overexpressed in multiple cancers including breast cancer37.
While enzymes regulating lipid synthesis are often expressed in low levels in most normal tissue (Clarke, 1993), they are overexpressed in multiple types of cancers.
It is overexpressed in multiple human cancers and has been proposed as an attractive anti-cancer target [24].
MCM3 is overexpressed in multiple malignancies, regarded a more sensitive tumour marker than Ki67, and 90% of mice injected with MCM3 transfected cells developed epithelial tumours within 6 weeks[28].
Similarly to other MMPs, MMP28 is overexpressed in multiple disease states [ 8].
