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The low coverage provided by fHbp could be overcome using a multicomponent vaccine.
We call this modeling difficulty the trifold identification problem and show that it may be overcome using a test based on the quasi-likelihood ratio (QLR) statistic.
However, major problems like cell survival, control of differentiation and engraftment remain and may be overcome using a tissue engineering strategy, which provides a 3D support to grafted cells improving their survival.
For example, it is shown how the loss of seeded cells arising from slow infiltration of vascular tissue can be overcome using a prevascularisation strategy consisting of seeding the scaffold with vascular cells.
Recently, Vandamme et al. demonstrated that resistance to everolimus could be overcome using a novel phosphoinositide-3 kinase (PI3K -Akt-mTOR inhibitor [12].
Taken together, the results obtained with the AnBUSDiC test demonstrate that the problems with unspecific digester gas formation can be overcome using a two-step test substance addition.
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Many of these challenges can be overcome using an observational approach that measures daily parent child interactions in real life.
Data shown in this paper demonstrate that the challenges in quantitation when incorporating TWIMS, which are associated with signal saturation, can be overcome using an alternative, MS2-based, label-free, absolute quantitation method.
That problem has now been overcome, using a network of recoverable seismometers deployed on the seabed by scientists from the Scripps Institution of Oceanography and the Woods Hole Oceanographic Institution.
Deficiencies in time control that have long stymied efforts to establish orbital effects on deglaciation are overcome using a new statistical test that focuses on maxima in orbital forcing.
The major problem, handling arbitrary variations in the model geometry, is overcome using a modified form of the Woodcock neutral-particle tracking algorithm.
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