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This chapter will address the second question by explaining that the missing links in each of the pre-design, design, and post-design phases can effectively be overcome based on the three competencies: (1) the competency for determining the boundaries of systems (machine, thinking space, etc).
Such concerns could be overcome based on subsequent research using a larger sample of older adults who are recruited for a focal effort on the construct validity of SPPB score inferences.
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Also, the sampling matrix condition is efficiently overcome based on probabilistic formulation [12 14].
If these challenges can be overcome, URFC based on proton exchange membrane (PEM) technology has potential for reducing the cost of overall hydrogen fuel cell system and can offer clean, reliable and onsite hydrogen and power generation.
These challenges can be overcome using approaches based on anchoring the overall alignment tensor frame on specific domains through paramagnetic alignment or helix elongation.
However, a number of technical hurdles must be overcome before therapies based on pluripotent human stem cells can enter the clinic.
Our analyses illustrate how the practical challenges of incorporating deterioration and allowing for measurement error might be overcome when basing NNTs on patient-reported continuous outcomes.
We call this modeling difficulty the trifold identification problem and show that it may be overcome using a test based on the quasi-likelihood ratio (QLR) statistic.
At the heart of these rational, but false models, interdependence is seen as a constraint (information theory) or experimental confound (cognitive models) that must be overcome to confirm models based on individuals.
The challenges in the next phase of the genetic studies of complex diseases will most likely be overcome by combinatorial approaches based on genetic association and functional characterization of candidate genes located within the intervals identified by GWAS.
Recent studies suggest that these limitations can be overcome by targeting strategies based on the conjugation of these proteins with ligands capable of delivering them to the tumor site, thereby allowing administration of lower doses and reducing systemic effects [ 1, 2].
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