IVDs have two distinct regions, the inner nucleus pulposus (NP) which is jelly-like and rich in glycosaminoglycans (GAGs) and the outer annulus fibrosus (AF) which is organized into highly collagenous lamellae.
These filaments are organized into highly ordered structures, forming bundles or three-dimensional networks.
Since gene expression profiles in human brain regions are organized into highly reproducible co-expression modules [ 12], it is important to determine which of these modules show evidence of preservation in blood.
Our suggestion is that gradually developing cumulative processes like aging affect a small proportion of the interactome, which has been proved to be organized into smaller scale highly inter-connected communities.
SMCs in the engineered vessel wall were organized into a highly lamellar structure, with cells separated by alternating layers of collagen fibrils.
The current implementation of the Neo-Darwinian model of evolution typically assumes that the set of possible phenotypes is organized into a highly symmetric and regular space equipped with a notion of distance, for example, a Euclidean vector space.
A literature review spanning product design, manufacturing, and supply operations management reveals several near-term research needs, which are organized into four highly promising foci addressing product architecture engineering, assembly/disassembly operation modeling, manufacturing process modeling, and joint optimization of life cycle activities.
My-Inflamome is organized into modules highly specialized in different biological processes relevant to heart repair.
A recent study reported that, on intestinal mucosal surface, bacterial community is organized into five highly conserved modules in human, two of them displaying distinct metabolic functionalities and being reciprocally associated with IBD.
