Sentence examples for be optimized for binding from inspiring English sources

The full con promoter sequence, derived by in vitro evolution, is likely to be optimized for binding to EσA.

The full con promoter sequence was derived from an in vitro evolution (SELEX) protocol optimizing for binding to Eco RNAP σS-holoenzyme, but subsequent analysis indicated the sequence appeared to be optimized for binding σ-holoenzyme as well (Gaal et al., 2001).

These previously identified peptides were not selected from all of the possible sequences and therefore may not be optimized for binding to MDM2.

Future analogs can be optimized for binding to the human MHC [ 28].

If specific and functional kinase- or phosphatase-substrate interactions are optimized for binding compared to promiscuous interactions, then changes in phosphorylation should occur faster on functional versus promiscuous substrates.

Expanding on the beneficial effects of MPL®, we have developed a series of formulations containing a synthetic molecule called Glucopyranosyl Lipid A (GLA), which is optimized for binding to the human MD2 molecule of the TLR4 complex.

This process can also be optimized for lignin recovery.

However, recent biochemical studies show that NikR's affinity for DNA is also dependent on potassium (8), and calculations examining metal stability, charge, and size preference suggest that these second metal binding sites are optimized for potassium binding (7).

MOs have been optimized for efficient binding to mRNA and generally have a length of 25 nucleotides.

These residues surround the hinge region at the RING0/RING1 interface that is optimized for pUb binding (Fig 3B, C, E and F).

Taken together, the NMR and crystal structures suggest that the crystal traps a conformation of the protein that is not the dominant one in solution but is optimized for ligand binding.