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Operators performing freehand compression must use a precise manual technique to generate high-quality elastograms, which can be optimised by referring to compression quality scales that are automatically computed and displayed in real time (Fig. 10).

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Informed by practical experiments, these flow conditions were optimised by subsequent mathematical modeling as shown in Fig. 2A.

Chromatographic variables were optimised by means of experimental design.

Sonication time and surfactant concentration were optimised by UV-vis spectroscopy and dynamic light scattering technique.

A mathematical model used by the team confirms that, given pygmy life expectancies, their growth and reproduction patterns have indeed been optimised by natural selection.

The workflow is optimised by opening the connecting door between the two suites.

The CR data was initially aligned using CLUSTAL X [52] and subsequently both datasets were optimised by visual inspection in a manual alignment editor [53].

To achieve this, contrast is optimised by combining dual echo T2W and proton density images [ 10].

act-detect's parameters are optimised by means of a λ,  μ-evolutionary algorithm [ 1, 51].

The HIV tests on the dried blood spots were optimised by use of paired serum samples and dried blood.

Initially PCR amplification conditions were optimised by separately varying magnesium chloride concentration, annealing temperature, primer concentration and DNA template concentration.

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