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However, as tamoxifen is also weakly estrogenic, it may not be optimally effective and increases the risk of endometrial cancer and stroke.
For a trauma system to be optimally effective, given limited available resources and the need for urgent care of the seriously injured, it is critical to utilize a method of differentiating those injury victims, who need the specialized expertise and resources available in trauma centres, from those who can be cared for adequately locally.
To be optimally effective, the availability of tailor-made clinical grade procedures is a prerequisite.
This study suggests that, in order to be optimally effective, regulatory T cell depletion should be used in association with other forms of immunotherapy The authors wish to thank all colleagues at MIMR for useful discussions.
This would permit peroxidase inhibition to be optimally effective under conditions in which COX inhibition is less active [ 160, 161].
The selected concentrations of the agents used were found to be optimally effective in previous studies [ 26, 28].
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Drugs are optimally effective in the therapeutic concentration range.
This information may be useful in designing novel measles vaccines that are optimally effective across human genetic backgrounds.
Evidence for the effectiveness of self-management interventions in chronic musculoskeletal pain is equivocal and it is not clear for which sub-groups of patients SM is optimally effective.
7 However, computerised decision support has also failed to improve practitioners' performance, 7 8 18 19 and in which circumstances and settings it is optimally effective is unclear.
The increasing level of collaboration on AMR at international level has been well recognized but as the support to countries to meet international standards and manage the threat posed by AMR increases even more coordination will be needed to ensure such support is optimally effective.
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