The second and more challenging issue is how to develop an institutional architecture such that tensions across the three sectors are optimally balanced to ensure stable relationship and sustainable governance.
This can be attributed to the fact that for larger subset sizes, the load may not be optimally balanced and some threads that were assigned disproportionately higher load might prolong the overall total execution time while other threads are idle.
A question worthy of more discussion is how sensitivity and specificity should be optimally balanced in expression profiles.
Since increasing N would also increase the ratio of false positives in profiles, it was empirically decided that the sensitivity and specificity of expression profiles were optimally balanced at N = 60.
Run orders that are optimally balanced for time trends usually involve huge costs due to the large number of factor level changes.
An algorithm is presented to construct cost-efficient cross-over designs that are optimally balanced for time trend effects.
Interestingly, in silico examination of potential cross-reaction as a function of siRNA length led to the conclusion that target specificity and low probability of off-target effects were optimally balanced for siRNAs of 21 nucleotides [ 23].
The sour, smoky, mysterious taste of dendê oil is optimally balanced by the briny tang of shellfish, the sweetness of coconut milk, the heady tropical aroma of cilantro and the zing of chilies.
The construction of run orders that are optimally balanced for time trend effects is based on maximization of the information on the parameters of interest whereas the parameters of the postulated time trend are treated as nuisance parameters.
Closely related is the minimum balance problem: Find a potential π : V(G →R such that the numbers slack e)≔π(w)−π v −c((v,w)) (e= v,w ∈E(G)) are optimally balanced: for any subset of vertices, the minimum slack on an entering edge should equal the minimum slack on a leaving edge.
