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The apical expression of TLR2 on tubular cells could be optimal for interaction with filtered or leaked stress ligands [30] [32] or with ligands that are expressed apically [33].
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It is also likely that the peptide substrates fluctuate between many different conformations in solution, only some of which are optimal for interaction with the transglutaminase, whereas the tethered sequences in the fusion protein context could be constrained in a more optimal conformation.
A temperature of 37 °C was found to be optimal for the MT1 interaction and was maintained constant during the measurements.
However, this commercially available assay may not be optimal for studying ligand PXR interactions because the chemical structure of Fluormone PXR (SXR) Green is proprietary information that is not publicly disclosed and Fluormone PXR (SXR) Green is available only as a component of the assay kit and at a prediluted concentration of 4 μM in 50% methanol/water.
A 20-kb window has previously been shown to be optimal for ERα enhancer-promoter interactions [ 31].
You might sum it up as classical liberal holism: what is optimal for one must be optimal for all.
† Previous studies have observed that polymers with WCAs between 65° and 80° are optimal for hPSC interaction.
Furthermore, the guanidinium group of the arginine-anchor is optimal for ionic interaction with all three H2A acidic side chains in the shared acidic-patch binding pocket.
A trinucleotide is a minimal weak template, and formation of a complementary pair of imperfect "triplets" (Fig. 1) can only occur if all available components are optimal for this interaction.
The case-only design is optimal for assessing multiplicative interaction when the genotype and environmental exposure are independent of one another.
The results of this study suggest that there is a threshold BG content which is optimal for osteoblast growth, and the interactions between PLAGA and BG may modulate the kinetics of Ca P formation and the overall cellular response.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com