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The method, which relies on matched filtering, should be optimal for detection of a known signal in the presence of Gaussian white noise.
The method is shown to be optimal for detection in the Neyman-Pearson sense, it returns an envelope spectrum comparable to the best that can be obtained by other means – which often require a careful pre-filtering step – from which fault frequencies can be identified, and it eventually returns the fault signal from which subsequent severity/health indicators can be computed.
CGH array may, however, not be optimal for detection of polyploidy/chromosome 17 polysomy because the data analysis is based on the Hidden Markov Model which may fail to uncover polyploidy.
This false-positive rate can be reduced by using long-echo MRS with TE at 97 ms with the use of three-dimensional volume-localized basis (VLB) spectra, which has been shown to be optimal for detection of 2HG [ 5, 6].
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This is due to the fact that contrary to the LRT receiver which is optimal for detection, GLRT receivers are sub-optimal receivers which generate estimates of the noise covariance matrix with more variance when primary data are used.
The present study we found low sensitivity of IFN-γ production following EC stimulation for differentiating into TST+ or TST− HHC but good discrimination between infection and disease following TB10.4 stimulation indicating that a longer-term stimulation is optimal for detection of active disease.
Overmeer et al. demonstrated that this marker combination is optimal for detection of CIN3 lesions [ 69].
After testing 100, 200, 400, 600, 800, and 1000 nM thrombin against 200 nM aptamer, we concluded that 400 nM thrombin was optimal for detection and resolution.
According to Bell-Krotoski [ 25] the 2.83 filament (target force 0.07 g) is optimal for detection of mechanical stimuli in most body areas with the exception of the foot sole, where a slightly stronger filament 3.61 (0.4 g) is recommended for normal subjects.
Therefore, the isolation window 526.3 ± 6 m/z was found to be optimal for the detection of both fragment ions.
The isolation window of 526.3 ± 6 m/z was found to be optimal for the detection of both fragment ions: 784.4 m/z and 794.4 m/z of native angiotensin II and the internal standard respectively.
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