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The histone methyltransferase Suv39h1 may be one critical factor responsible for this difference between HT1080 and HeLa alphoid DNA chromatin.
These findings suggest that sampling strategy should be one critical factor when designing epidemiologic studies that include biomonitoring measures of urine specimens.
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That must be our goal as well, and compensation is one critical factor.
Niemann Pick C1 (NPC1) is one critical host factor, and there may be others unidentified; ultimately these trigger GP2 into its active fusogenic conformation.
NF-κB is one critical transcription factor required for the expression of many cytokines involved in the pathogenesis of acute lung injury [ 26, 27, 28, 29, 30, 31, 32, 33, 34, 35].
Minimizing energy cost is one critical factor animals select gaits that cost less energy to get from point A to point B (e.g. Hoyt & Taylor 1981; Bertram & Ruina 2001).
He added, "Lowering the price of medicines, however, is only one critical factor in what must become a much broader and more urgent effort".
Although the precise molecular mechanism of LSC-mediated resistance to current therapies has not been fully elucidated, one critical factor might be the quiescence of LSC that allows this population cells to evade the targeting by current therapies.
Experts agree that the change is due to one critical factor: money.
One critical factor is how many rats are resistant to the disease.
In the first application, the sensor was successfully used to measure one critical factor called augmentation index (AI) that is related to arterial stiffness and cardiovascular diseases [7].
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