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For this work to be of sufficient impact for publication in eLife experiments to demonstrate a specific role of RBM47 in metastasis, as opposed to general cell proliferation, are required.
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Ongoing and future climate change may be of sufficient magnitude to significantly impact global forest ecosystems.
We believe that the design of the study, the randomisation procedure and outcome measurements will be of sufficient strength and quality to evaluate the impact of comprehensive geriatric assessment on mobility and other relevant outcomes in hip fracture patients.
In conclusion we believe that study design, randomisation procedure and outcome measurements will be of sufficient strength and quality to evaluate important impacts of CGA during the index stay on mobility and other relevant outcomes in hip fracture patients.
An epidural hematoma forms when the head impact is of sufficient force to either pull the meninges away from the inner table of the skull or cause a skull fracture.
Long-lived species may also be limited by environmental catastrophes, such as drought, flood, fire or disease, which can cause sudden and, at times, significant shifts in population size and dynamics over a very short time, if the effects of such catastrophic impacts on demographics are of sufficient frequency and intensity [5].
Several theoretical studies have demonstrated that the relatively slow speed of kill of entomopathogenic fungi can be sufficient to impact on malaria transmission since the extrinsic incubation period of the malaria parasite within the mosquito (typically 10 14 days in high transmission settings) creates a window of several days for the fungus to act [19], [31], [42], [43].
We suggest that these remnants would retain Apo-Fur activity; and that their binding activity, although weakened by the inability to dimerize, nevertheless should be sufficient to impact on transcription of genes affecting Mtz susceptibility.
The second affect is of greater impact.
Humanities and the social sciences are not having a sufficient impact on public policy-making, the British Academy BAA) warned today.
We note that despite telecommunications being a key critical infrastructure sector, we did not consider there to be sufficient documentation of impacts or mitigation guidance to create a robust poster.
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