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Hence, as briefly described below ("Strategies targeting the mevalonate pathway and cholesterol synthesis in cancer" section), targeting the mevalonate pathway may be of potential relevance in cancer therapy.
We believe this approach to be of potential relevance especially in the context of oncological whole-body investigations where the required AIF information is available in the field of view (aorta or left ventricle).
Moreover, the effect of small molecules that block the entry of pyruvate to the mitochondrial TCA cycle, such as dichloroacetate, a PDK1 inhibitor, may be of potential relevance [109, 218, 224].
This molecule and its link with endoplasmic reticulum stress could be of potential relevance in the field of organ transplantation.
This may be of potential relevance because we have shown in previous cell fractionation experiments that GFP-FEZ1 can be found in the nuclear fraction [26].
Whether or not it may be of potential relevance in the clinical setting remains to be established, and experiments analyzing the ganglioside profile in primary human liver tumors in comparison with healthy liver biopsies may help to clarify this important issue.
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The "best fit" method of framework synthesis offers a pragmatic means of conducting rapid qualitative evidence synthesis and generating models and, potentially, programme theories, and is of potential relevance both to researchers and policy-makers.
While the fact he had been married was of potential relevance, this could have been reported without identifying her.
Considering multiple ligand binding modes is of potential relevance to studying ligand recognition, but is generally ignored by currently available techniques.
An important mechanism contributing to the efficient allelic-drive we observed, which is of potential relevance to field applications, is the phenomena of lethal mosaicism, which dominantly eliminates all NHEJ-induced drive-resistant non-functional loss-of-function alleles of an essential gene such as Notch.
Hence the identified region is of potential relevance for the epigenetic silencing of ABCB1 expression.
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be of pathophysiological relevance
be of great relevance
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be of potential application
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be of potential advantage
be of especial relevance
be of potential harm
be of potential benefit
be of therapeutic relevance
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